News and events
2024-02-29
One of the tasks of POLONEZ BIS is to develop the research career of the program fellows. In this regard, Dr. Taisiia Yurchuk took part in the 2-month EIT Food We Lead Food program, which is part of the RIS Professional Development program. Within the framework of it, the participants had the opportunity not only to listen to lectures given by coaches and leading specialists in various areas of business and Food industry, but also had the opportunity to participate in various practical activities aimed at increasing the effectiveness of team management and its effective development, motivating their employees, developing entrepreneurial competencies, leadership qualities and systemic mind ship.
One of the tasks of POLONEZ BIS is to develop the research career of the program fellows. In this regard, Dr. Taisiia Yurchuk took part in the 2-month EIT Food We Lead Food program, which is part of the RIS Professional Development program. Within the framework of it, the participants had the opportunity not only to listen to lectures given by coaches and leading specialists in various areas of business and Food industry, but also had the opportunity to participate in various practical activities aimed at increasing the effectiveness of team management and its effective development, motivating their employees, developing entrepreneurial competencies, leadership qualities and systemic mind ship.
2023- 06-25
Dr Taisiia Yurchuk participated in the 59th meeting of the Society of Low Temperature of Biology (SLTB) which took place on September 19-22 at the University of Vigo. Dr Yurchuk reported the efficiency of using direct in straw thawing of bovine embryos after vitrification either in Cryotec or open pulled straws (OPS). She concluded that bovine embryos have higher rates of survival and development, as well as levels of embryonic cell DNA integrity, after vitrification in OPS and direct straw thawing compared to slow freezing. These finding can be useful for cattle breeding centers.
The organizers of the meeting, led by Dr. Estefania Paredes, held a photo contest dedicated to Cryobiology. Dr. Yurchuk's photo taken in Poland at the Institute of Animal Reproduction and Food Products of the Polish Academy of Sciences was awarded 3rd place.
Dr Taisiia Yurchuk participated in the 59th meeting of the Society of Low Temperature of Biology (SLTB) which took place on September 19-22 at the University of Vigo. Dr Yurchuk reported the efficiency of using direct in straw thawing of bovine embryos after vitrification either in Cryotec or open pulled straws (OPS). She concluded that bovine embryos have higher rates of survival and development, as well as levels of embryonic cell DNA integrity, after vitrification in OPS and direct straw thawing compared to slow freezing. These finding can be useful for cattle breeding centers.
The organizers of the meeting, led by Dr. Estefania Paredes, held a photo contest dedicated to Cryobiology. Dr. Yurchuk's photo taken in Poland at the Institute of Animal Reproduction and Food Products of the Polish Academy of Sciences was awarded 3rd place.
2023- 09-04
Prof. Dariusz J. SKARZYNSKI and Prof. Kiyoshi OKUDA organized 5th seminar "Cutting-edge Reproductive: Bridges to the Future of Research and Cooperation" for the development of scientific and research cooperation between the Polish and Japanese Academies of Sciences, which was held on September 4-6 at Iwate University in Marioka, Japan. Representatives of both Academies of Sciences made reports on common subjects. Thus, in the section "Oogenesis and development of embryos of early stages of development", Dr. Taisiia YURCHUK (Institute of Animal Reproduction and Food Research of the PAN) made a report together with Kanako MOROHAKU (Shinshu University) and Takashi FUJII (Iwate University) and Dr. Piotr PAWLAK (Poznan University of Life Science). The title of Dr. YURCHUK presentation was “Recent progress in bovine embryo cryopreservation for cattle breeding and provoked many interesting questions and discussions”. She reported about the achievements of the development of animal husbandry with the use of assisted reproductive technologies and cryotechnologies in recent years. According to the annual International Embryo Technology Society (IETS) statistics the data of the embryo industry on the four most representative farm animal species increase every year, with more than 2 million embryos collected in 2021. The most remarkable increase occurred in cattle breeding. Over 1.5 million in vitro-produced (IVP) embryos were recorded, an increase of 31.5% compared with 2020 (1,521,018 vs. 1,156,422, respectively). Despite the embryos produced in vitro are 80% of the whole amount there are have low cryotolerance. Therefore, Dr. YURCHUK proposed two main strategies to overcome the problems that seek better and more stable results regarding the cryopreservation of IVP embryos. The first refers to the induction of modifications in embryo cells so that they become more cryotolerant, such as changes in culture conditions to minimize high lipid content. The other refers to changes in cryopreservation methods, such as changes in the concentration and type of cryoprotectant, and changes in cooling times and temperatures. Then, Dr. YURCHUK reported her own results after using different methods of cryopreservation of IVP embryos. Dr. FUJII, Dr. MOROHAKU and Dr. PAWLAK reported about differences between IVP and in vivo derived embryos and the improvement of their culture conditions. Common subject in the researches sparked interesting questions and discussion among delegates.
We hope for further fruitful research cooperation established by Prof. D. SKARZYNSKI and Prof. K. OKUDA 20 year ago.
Prof. Dariusz J. SKARZYNSKI and Prof. Kiyoshi OKUDA organized 5th seminar "Cutting-edge Reproductive: Bridges to the Future of Research and Cooperation" for the development of scientific and research cooperation between the Polish and Japanese Academies of Sciences, which was held on September 4-6 at Iwate University in Marioka, Japan. Representatives of both Academies of Sciences made reports on common subjects. Thus, in the section "Oogenesis and development of embryos of early stages of development", Dr. Taisiia YURCHUK (Institute of Animal Reproduction and Food Research of the PAN) made a report together with Kanako MOROHAKU (Shinshu University) and Takashi FUJII (Iwate University) and Dr. Piotr PAWLAK (Poznan University of Life Science). The title of Dr. YURCHUK presentation was “Recent progress in bovine embryo cryopreservation for cattle breeding and provoked many interesting questions and discussions”. She reported about the achievements of the development of animal husbandry with the use of assisted reproductive technologies and cryotechnologies in recent years. According to the annual International Embryo Technology Society (IETS) statistics the data of the embryo industry on the four most representative farm animal species increase every year, with more than 2 million embryos collected in 2021. The most remarkable increase occurred in cattle breeding. Over 1.5 million in vitro-produced (IVP) embryos were recorded, an increase of 31.5% compared with 2020 (1,521,018 vs. 1,156,422, respectively). Despite the embryos produced in vitro are 80% of the whole amount there are have low cryotolerance. Therefore, Dr. YURCHUK proposed two main strategies to overcome the problems that seek better and more stable results regarding the cryopreservation of IVP embryos. The first refers to the induction of modifications in embryo cells so that they become more cryotolerant, such as changes in culture conditions to minimize high lipid content. The other refers to changes in cryopreservation methods, such as changes in the concentration and type of cryoprotectant, and changes in cooling times and temperatures. Then, Dr. YURCHUK reported her own results after using different methods of cryopreservation of IVP embryos. Dr. FUJII, Dr. MOROHAKU and Dr. PAWLAK reported about differences between IVP and in vivo derived embryos and the improvement of their culture conditions. Common subject in the researches sparked interesting questions and discussion among delegates.
We hope for further fruitful research cooperation established by Prof. D. SKARZYNSKI and Prof. K. OKUDA 20 year ago.
2023- 06-25
Dr Yurchuk participated in the European Society of Human Reproduction and Embryology meeting - ESHRE 2023 and presented the poster "Are cumulus cells required during in vitro maturation of human oocytes at the germinal vesicle stage?"
Dr Yurchuk participated in the European Society of Human Reproduction and Embryology meeting - ESHRE 2023 and presented the poster "Are cumulus cells required during in vitro maturation of human oocytes at the germinal vesicle stage?"
Study question: Does the presence of cumulus cells affect the in vitro maturation (IVM) rate of human oocytes at the germinal vesicle (GV) stage obtained in vivo?
Summary answer: The oocyte maturation and fertilization rates are higher in the presence of cumulus cells (CC) comparing with their absence in the culture system.
What is known already: According to the ESHRE guidelines IVM is currently not considered experimental, but nevertheless it is not very often used in reproductive medicine clinics. Accumulated data of more than 30 years of existence of IVM method can present to us how effective is the level of oocytes maturation in vitro obtained by aspiration follicles in vivo. Some studies reported that oocytes were matured after denudation, and in others they are cultured in cumulus oocyte complexes or in the presence of CC. Therefore a comparison of oocyte maturation at the GV stage with and without CC was performed in this study.
Participants/materials, setting, methods: Participants were women undergoing infertility treatment with IVM. All oocytes from the included studies were obtained by follicular aspiration in vivo.
Main results and the role of chance: A preliminary screening of the word combination “human oocyte in vitro maturation” yielded 355 results, from which 42 were original publications with full-text. Selected papers included a full description of the stimulation protocol, maturation medium, and the group of immature oocytes consisted of gametes only at the GV stage. A total of 24,649 GV oocytes were examined for IVM rate. The average of oocyte maturity was 61.5 ±10.7%. However, the distribution of oocyte maturation . data depending on the presence or absents of CC in the culture media. The maturation rate was higher in oocytes with cumulus cells than in denuded oocytes without cumulus (64.7% vs 53.5%, respectively, p<0.05). The fertilisation rate had the same tendency (69.2% vs. 59.5%, p<0.05). However, there was no significant difference between the groups in embryo development up to the cleavage stage (74.9% vs 76.5%, p>0.05). Unfortunately, there are very only a few studies that provide data on the more advanced . stages of embryo development as a blastocyst, which does not allow a large sample to be made for any IVM method.
T Yurchuk, V Piniaiev, M Petrushko. P-118 Are cumulus cells required during in vitro maturation of human oocytes at the germinal vesicle stage? a systematic review, Human Reproduction, Volume 38, Issue Supplement_1, June 2023, dead093.482, https://doi.org/10.1093/humrep/dead093.482
Summary answer: The oocyte maturation and fertilization rates are higher in the presence of cumulus cells (CC) comparing with their absence in the culture system.
What is known already: According to the ESHRE guidelines IVM is currently not considered experimental, but nevertheless it is not very often used in reproductive medicine clinics. Accumulated data of more than 30 years of existence of IVM method can present to us how effective is the level of oocytes maturation in vitro obtained by aspiration follicles in vivo. Some studies reported that oocytes were matured after denudation, and in others they are cultured in cumulus oocyte complexes or in the presence of CC. Therefore a comparison of oocyte maturation at the GV stage with and without CC was performed in this study.
Participants/materials, setting, methods: Participants were women undergoing infertility treatment with IVM. All oocytes from the included studies were obtained by follicular aspiration in vivo.
Main results and the role of chance: A preliminary screening of the word combination “human oocyte in vitro maturation” yielded 355 results, from which 42 were original publications with full-text. Selected papers included a full description of the stimulation protocol, maturation medium, and the group of immature oocytes consisted of gametes only at the GV stage. A total of 24,649 GV oocytes were examined for IVM rate. The average of oocyte maturity was 61.5 ±10.7%. However, the distribution of oocyte maturation . data depending on the presence or absents of CC in the culture media. The maturation rate was higher in oocytes with cumulus cells than in denuded oocytes without cumulus (64.7% vs 53.5%, respectively, p<0.05). The fertilisation rate had the same tendency (69.2% vs. 59.5%, p<0.05). However, there was no significant difference between the groups in embryo development up to the cleavage stage (74.9% vs 76.5%, p>0.05). Unfortunately, there are very only a few studies that provide data on the more advanced . stages of embryo development as a blastocyst, which does not allow a large sample to be made for any IVM method.
T Yurchuk, V Piniaiev, M Petrushko. P-118 Are cumulus cells required during in vitro maturation of human oocytes at the germinal vesicle stage? a systematic review, Human Reproduction, Volume 38, Issue Supplement_1, June 2023, dead093.482, https://doi.org/10.1093/humrep/dead093.482
2023-06-19
Principal Investigator and the Mentor of the project participated in the Kick-off meeting organized by NCN for the POLONEZ BIS 2 call
Principal Investigator and the Mentor of the project participated in the Kick-off meeting organized by NCN for the POLONEZ BIS 2 call
2023-05-18
Project Investigator organised workshorp and lecture "Is there life after -196?” for children and adults from Ukraine who ended up in Poland as a result of russian aggression.
Project Investigator organised workshorp and lecture "Is there life after -196?” for children and adults from Ukraine who ended up in Poland as a result of russian aggression.
